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June 11, 2009

The Digital Pathology Revolution: Breaking the Glass Ceiling

Article preview reprinted from Start-Up - May, 2009

Among diagnostic specialties, anatomic pathology is the last holdout against the digital revolution. Pathologists still detect disease by looking at tissue samples on a glass slide through a microscope, just as they have done for a hundred years. But in the last couple of years, start-up companies have begun to break the bondage of pathologists to slides. Their solution: platforms for digitizing slides so they can be accessed through computer networks by clinicians anywhere in the world. Two start-ups, Aperio and BioImagene, have led the way and now all the big imaging manufacturers, the microscope companies and biomarker developers want in. Read more...

The Digital Pathology Revolution: Breaking the Glass Ceiling

Article preview reprinted from Start-Up - May, 2009

Among diagnostic specialties, anatomic pathology--the sub-specialty that detects disease by identifying morphologic features in tissue--is the last holdout against the digital revolution. Pathologists still hold to the time-worn tradition of looking at a glass slide under a microscope. But in the last couple of years, start-up companies have begun to break the bondage of pathologists to slides. Their solution: platforms for digitizing slides so they can be accessed through computer networks to clinicians anywhere in a hospital system--or in the world, for that matter. When slides are converted to a digital format, pathologists don't have to wait for FedEx shipments of glass slides, collate them in trays, read them one at a time, or ship them somewhere else for a second opinion. Digitization offers obvious workflow efficiencies, and it also makes possible faster and more accurate diagnoses because slides can be displayed on a screen alongside others that can be easily retrieved from digital archives to provide a new perspective, expert second opinions can be quickly and easily sought, and computer algorithms can be applied to the interpretation of images.

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Companies mentioned in this article:

Aperio Technologi es Inc.

BioImagene Inc.

Carl Zeiss AG

Clarient Inc.

Dako AS

Genetix Group PLC

Hologic Inc.

R2 Technology Inc.

Median Technologies

Nikon Corp.

Olympus Corp.

Roche

Roche Diagnostics

Ventana Medical Systems Inc.

Royal Philips Electronics NV

Healthcare Solutions Group

Siemens AG

University of Pittsburgh

University of Pittsburgh Medical Center

iCAD Inc.



START-UP: No publication reviews leading edge companies and technology better than START-UP. Each issue of START-UP profiles the most important new product companies, identifies the hottest technology areas, reviews funds flowing into private companies and investment trends, and reports on university tech transfer licensing. Industries covered: pharmaceuticals, biotechnology, medical equipment & devices, and in vitro diagnostics. Subscribe to START-UP.

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