Article preview from Start-Up - May 1, 2011
Intertwining technologies of a miniature left ventricular pacemaker with a leadless electrode from Israeli-based Sirius Implantable Systems Ltd. may someday improve the quality of pacing therapy and reduce the incidence of complications associated with conventional electrical wiring for standard pacemakers. Sirius' unique self-powered pacemaker and the leadless electrode will be implanted on the left side of the heart by minimally invasive surgery and can be matched with any standard pacing device in the market.
Article preview from Start-Up - May 1, 2011
Intertwining technologies of a miniature left ventricular pacemaker with a leadless electrode from Israel-based Sirius Implantable Systems Ltd. may someday improve the quality of pacing therapy and reduce the incidence of complications associated with conventional electrical wiring (leads) for standard pacemakers. Existing pacing therapies are complicated by poor hemodynamics, atrial fibrillation (AF) and heart failure from pacing the right side of the heart, and a by a high failure rate of the leads. In fact, leads are the most commonly recalled component of a pacing system.
The company's unique self-sustaining pacemaker and the leadless electrode will be implanted on the left side of the heart in a minimally invasive procedure, and it can be matched with any standard pacing device in the market.
A miniature pacemaker or leadless electrode may be powered by one of three ways: a battery, transfer of energy or generation of energy. Sirius has chosen the latter by developing a microgenerator that harnesses the mechanical movement of the heart to generate electrical power for its pacemaker. "Our proprietary implantable microgenerator will serve as a life-long renewable power source for implantable cardiac stimulators," says Dan Gelvan, founder and CEO of Sirius, noting that two to 10 times the energy required by a pacemaker may be generated from cardiac motion.
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